Abstract:Objective：This study selected the inpatient data of postmenopausal uterine leiomyoma patients in a certainhospital in Beijing from 2019 to 2021 to analyze their cost level，cost structure and service utilization. Methods：Through SPSS 26.0，t test and chi square test were used to analyze the menopausal group and perimenopausal group. Results：The average hospitalization expense of hysteromyoma patients was 15，092.41yuan，the proportion of medical insurance reimbursement was 65.27%，the average personal burden was 5，265.79 yuan. Comparison of menopausal group and perimenopausal group，the cost of anesthesia，the cost of examination and treatment，the number of days in hospital，the number of operations，the time of operations，the distribution of age，the number of years of illness，the clinical manifestation，the way of operations and the complication of hypertension，there was no significant difference.In hospitalization cost，drug cost，postoperative days，postoperative bleeding volume，operative methods，medical diseases and other diseases，，there was no significant difference. Conclusion：The peak age of postmenopausal uterine leiomyoma is 57 to 58 years old，and the cost burden continues to increase. It is suggested that patients pay close attention to clinical symptoms，actively strengthen physical examination，and improve the health level of elderly women.