Abstract:Objective：To explore the influence of WeChat platform for health education of blood donation on the awareness and recruitment of unpaid blood donation. Methods：Questionnaire was used to investigate the awareness of voluntary blood donation among 2，914 blood donors who made appointments and successfully donated platelets on WeChat platform（observation group）and 2，900 blood donors who spontaneously donated platelets to the blood center（control group）at the same time，and the relevant data of volunteers who participated in monocollecting plateletsblood donation from July 2018 to July 2020 in our center were analyzed retrospectively. Results：The knowledge score of unpaid blood donation in the observation group（42.76±2.85）was significantly higher than control group（35.72±4.83），the difference was statistically significant（P < 0.05）. From August 2019 to July 2020，there were 2531 platelets collected for apheresis，an increase of 560.8% compared withthat from July 2018 to July 2019. From August 2019 to July 2020，there were 38 repeated apheresis platelets，an increase of 15.4% over that from July 2018 to July 2019. Conclusion：The WeChat platform of health education for blood donation can improving the cognition degree of unpaid blood donation，improving the recruitment effect and improving the repetition rate of monocollecting platelets.