Abstract:Objective：Through the empirical analysis and investigation on the job satisfaction of general practitioners（GPs）in Jiangsu Province，to find out the job satisfaction and influencing factors among them. Methods：From April to May 2020，1400 general practitioners（GPs）were selected for a questionnaire survey，which included social demographic characteristics and job satisfaction. MinnesotaSatisfaction Questionnaire（MSQ）was used to explore the influencing factors of job satisfaction，including satisfaction with working conditions，leadership，responsibility，external rewardsbyone-way ANOVAand logistic regression analysis. Results：1 308（93.4%）questionnaires were obtained. The average total score of job satisfaction was（75.22±15.01），and 442（33.8%）of general practitioners had a high total score（≥80）. The overall average score of job satisfaction byworking conditions，leadership，responsibility and external rewards，respectively（23.06±4.62）、（7.52±2.06）、（23.57±4.39）、（21.06±5.29）.The logistic regression analysis showed that，age，work unit，administrative duties，frequency of physical exercisewere the major factors affecting overall job satisfaction. Conclusion：The degree of job satisfaction needs to be improve. It is suggested continue to strengthen policyof support for general practitioners，so as to stabilize and continuously improve their job satisfaction.