Abstract:Objective：To analyze the current situation and weakness of archives management of large equipment in disease control institutionand provide solutions and advice for archives management of large equipment. Methods：From the procedures of procurement，acceptance inspection，usage and operation，the archives of large equipment were managed according to categorization and the contents and module of archives information were consolidated with electronic information，which in turn to facilitate the standardization and systematization of archives management of large equipment. Results and Conclusions：High quality of archives management of equipment is no doubt one of the most important section in constructing the quality system among disease control institution，which could ultimately improve the economic and social benefits for disease controlinstitution.