Abstract:Objective：To explore the pathway for public hospitals to transform external major strategic tasks into internal development momentum. Methods：A longitudinal single-case study was conducted on a certain high-level children’s hospital in Jiangsu Province，analyzing its process and results of embedding the major construction task into daily operations during the 2023-2025 period. Results：Through a strategic integration management mechanism featuring four-dimensional integration of goals，resources，performance，and culture. The hospital has achieved remarkable results in six major areas：the ability to solve complex and critical illnesses，the construction of disciplinary brands，scientific research and innovation，talent attraction and cultivation，operational efficiency，and regional influence，with 51 of 54 evaluation indicators met（94.44%）. Conclusion：Strategic integration management effectively resolves the strategy-operation disconnect and achieves a transformation from task-driven to mechanism-integrated approaches，serving as an effective pathway for promoting high-quality development in public hospitals.