Abstract:Objective：This study examines the design and implementation effects of a comprehensive disciplinary target management responsibility system based on contract management theory，using a certain grade A tertiary pediatric hospital as the research subject. Methods：A differentiated target management system was constructed，encompassing four dimensions（medical quality and safety，scientific research，education，and patient satisfaction）. Longitudinal comparative analysis was conducted to evaluate post-implementation outcomes. Results：Following implementation，the system significantly advanced disciplinary development，with structural optimization in medical quality and safety，enhanced scientific and educational innovation capabilities，and improved patient satisfaction. Conclusion：Differentiated management effectively addressed the limitations of uniform assessment approaches. The dual-track incentive mechanism achieved incentive compatibility，while the monthly-annual evaluation system substantially improved process management efficiency.