Abstract:Objective：This study employs a 3D printing simulation training method to enhance the nasal endoscopy skills of otolaryngology residents. Methods：Twelve participants undergoing standardized residency training in the Department of Otolaryngology at Gulou Hospital in Nanjing from September 2021 to June 2023 were selected for the study. The training utilized nasal endoscopy-based 3D printing simulation. A comparative analysis of pre- and post-training scores for hand-eye coordination exercises，powered resection system exercises，skull base drilling exercises，and 3D printing model simulation exercises revealed a significant improvement in post-training scores（P < 0.05）. Results：Feedback from the survey indicated a 90% mastery rate of 3D simulation training. The overall knowledge mastery rate was reported at 78%. A 93% overall satisfaction rate，and a 97% desire among participants to attend similar training again. Conclusion：Establishing a nasal endoscopy 3D printing simulation training system provides a superior learning platform for otolaryngology residents，enhancing their nasal endoscopy skills.