Abstract:Objective：To analyze 675 medical malpractice cases and provide countermeasures for continuous improvement of medical quality. Methods：The information of 675 medical malpractice cases handled by a medical liability insurance underwriting agency in Nanjing in 2022 was collected. The characteristics，high-risk departments，medical staff's negligence reasons，and violation of medical core systems in the treatment process were analyzed to identify high-risk factors in the medical institutions' treatment process. Results：The study found that elderly patients，inpatients，and surgical patients in tertiary medical institutions were high-risk groups for medical disputes，and obstetrics and gynecology，orthopedics，general surgery，emergency department，and cardiothoracic surgery were high-risk departments. Operating/procedure-related negligence was the main reason for medical disputes，and there were problems with the implementation of core medical systems such as consultation system and medical record management system. Conclusion：Medical institutions should focus on high-risk factors in medical disputes and establish a comprehensive quality management mechanism for continuous improvement of medical technology and medical quality and safety.