目的：分析江苏省某三级医院减重代谢手术患者的住院费用构成及其影响因素，为加强医院费用管理，减轻手术患者疾病经济负担提供依据。方法：选取2020年1月—2021年12月在该医院进行减重代谢手术患者的病案数据资料，采用描述性统计法分析住院费用构成和变化趋势，使用多元回归分析对住院费用的影响因素进行分析。结果：共纳入减重代谢手术患者1 552例，次均住院费用为4 9284.98±5 368.26元，平均住院天数为5.06±1.78天，住院费用的主要组成部分是卫生材料费、药品费和手术费；患者住院费用的影响因素包括性别、年龄、住院天数、BMI、糖尿病史、主手术方式以及是否合并附加手术（P＜0.05）。结论：医院应建立科学合理的临床路径，加强医用耗材的使用监管，降低患者的疾病负担。管理部门需进一步推进高值医用耗材集中带量采购，并适当提高手术类、治疗类医疗服务项目价格，突出体现医疗技术的劳动价值。

Objective：To analyze the hospitalization costs and its influencing factors of patients with bariatric and metabolic surgery in a tertiary hospital in Jiangsu Province，to provide basic evidence for reducing the economic burden and controlling hospitalization expenses. Methods：The medical record data of patients with bariatric and metabolic surgery in a tertiary hospital in Jiangsu Province from January 2020 to December 2021 were selected for data analysis. Descriptive statistics was used to analyze the composition of hospitalization expenses，and multiple regression analysis was used to analyze the influencing factors. Results：A total of 1，552 patients with bariatric and metabolic surgery were included in this study. The total hospitalization expenses was 49 284.98±5 368.26 yuan，and the average length of stay was 5.06±1.78 days. The main components of expenses were the cost of hygiene materials，drug costs and operation costs. The results of multiple regression analysis showed that the influencing factors of hospitalization expenses of bariatric and metabolic surgery included gender，age，length of stay，BMI，diabetes，main surgical method and additional surgery（P < 0.05）. Conclusion：Hospitals should establish scientific and reasonable clinical pathways and strengthen the supervision of the use of medical consumables funds to effectively reduce the economic burden of patients. Moreover，administrative departments should promote the centralized procurement for high-value medical consumables and appropriately raise the prices of surgical and therapeutic medical services to demonstrate the labor value of medical technology.