Abstract:Objective：In the“Healthy China” strategy and based on the “System of Health Accounts 2011”，the current health expenditure of Guizhou Province in 2020 were calculated. Methods：Based on the “Health Expense Accounting System 2011” and combined with the actual situation of the health work in Guizhou province，the functional method was used to calculate the current health expenditure in 2020 from the overall situation of current health expenditure，financing plan，direction of institutions，service functions，beneficiaries and other dimensions. Results：In 2020，the current health expenditure of Guizhou Province was 117.75 billion yuan，accounting for 6.61% of the GDP of Guizhou Province in 2020，and the per capital current health expenditure reached 3，056.06 yuan. Among them，government programs and compulsory health financing amount was 70.814 billion yuan，accounting for 60.14%.The family health expenditure plan raised 34.3 billion yuan，accounting for 29.13% of the total；87.306 billion yuan went to hospitals，accounting for 74.15%；The cost of treatment was 95.769 billion yuan，accounting for 81.33% of current health expenditure. Conclusion：The current health expenditure in Guizhou Province has increased，but the economic burden of medical treatment is still heavy. The cost of treatment services has risen rapidly，and the phenomenon of “prevention is less important than treatment” still exists. We can increase the government’s health investment in the cost of preventive services in Guizhou Province，enhance our capacity to respond to public health emergencies，promote the sinking of medical resources to grassroots medical institutions，and further optimize the service function and institutional distribution of current health costs.