Abstract:Objective：Through the systematic data analysis of medical adverse events in a certainhospital from 2017 to 2020，combined with the use of professional interviews，problems in management are found，corresponding countermeasures and suggestions are put forward. Methods：Retrospective analysis was used to analyze 1，117 events collected by the medical safety adverse event management system in a certainhospital from January 1，2017 to December 31，2020，andexpert interviews were conducted with 12 the heads of clinical departments，medical staff and administrative staff. Results：The reporting rate of grade Ⅲ and Ⅳ adverse medical events was high，and the number of reported cases in general surgery，orthopedics，gynecology，obstetrics and other operating departments was high. It was concluded that the main reason for underreporting and concealing adverse medical events wasworrying about the accountability of functional departments，causing disputes and affecting the quality assessment score of the department.The main problems in management are the lack of awareness of reporting，and the lack of tracking and rectification. Conclusion：To improve the medical and nursing risk awareness，improve the closed-loop management process system，strengthen the two-level supervision of the hospital and department，and build a harmonious and safe cultural atmosphere to improve the reporting rate of medical adverse events.