目的：了解南京市江北新区影响预防接种异常反应补充保险投保的主要影响因素。方法：2020年6月-9月期间在南京市江北新区范围内通过随机抽样的方法开展预防接种补充保险是否投保的调查问卷。对收集的调查问卷进行χ2单因素分析和logistic多因素回归分析。结果：共收集700份调查问卷，有效调查问卷633份。χ2单因素分析结果表明儿童月龄（P < 0.05）、是否独生子女（P < 0.05）、家长的年龄（P=0.001）、职业（P=0.011）、家庭收入水平（P=0.017）、是否购买商业医疗保险（P < 0.05）与是否购买补充保险方面有具有统计学意义。Logistic数据分析表明月龄小于6月的儿童（OR=4.861，95%，CI：3.020~7.824）、独生子女（OR=1.922，95%，CI：1.281~2.885）、父母年龄在30-35周岁（OR=1.032，95%，CI：0.606~1.757）、父母为事业单位员工（OR=1.000）、家庭年收入在20万元以上（OR=1.000）、购买商业医疗保险的家庭（OR=2.036，95%，CI：1.418~2.923）具有更强的投保意向和更积极的投保行为。结论：被调查人的年龄、职业和家庭收入是预防接种异常反应补充保险投保行为中的主要控制因素。

Objective：To understand the main influencing factors of supplementary insurance for abnormal vaccination response in Jiangbeinew areaof Nanjing. Methods：A questionnaire was carried out by random sampling in Jiangbei new area of Nanjing during June to September in 2020. The collected questionnaires were analyzed χ2 univariate analysis and logistic multivariate regression analysis. Results：700 questionnaires were collected in Jiangbei new area，and 633 were effective. χ2 univariate analysis showedthatthereweresignificantdifferencesinchildren’s month age（P < 0.05），whether they were the only child（P<0.05），parents’age（P=0.001），occupation（P=0.011），family income level（P=0.017），whether they bought commercial medical insurance（P < 0.05），and whether to buy supplementary insurance. Logistic data analysis shows that children less than 6 months old（OR=4.861，95%，CI：3.020~7.824），only child（OR=1.922，95%，CI：1.281~2.885），parents aged 30-35 years old（OR=1.032，95%，CI：0.606~1.757），parents who are employees of institutions（OR=1.000），families with an annual family income of more than 200，000 yuan（OR=1.000）and families who buy commercial medical insurance（OR=2.036，95%，CI：1.418~2.923）have strong insurance intention and behavior. Conclusions：Ageoccupation and family income were the main controlling factors for the behavior of the supplementary insurance for abnormal reaction to vaccination.