Abstract:Objective：To investigate the cognition of clinical application of new antitumor drugs among clinicians in a certaingrade-A tertiaryhospital in Jiangsu province，and to put forward corresponding countermeasures and suggestions for the existing problems in the management. Methods：According to the guiding Principles for the Clinical Application of Novel Antitumor Drugs（2020 edition），a questionnaire and interview outline were made by ourselves. Questionnaire survey and interview were conducted for clinicians and managers in the hospital respectively. Descriptive statistics，goodness of fit test and Chi-square test were used to analyze the cognitive situation. Results：Among the participating clinicians，66.99% had a high degree of cognition on the basic principles and management requirements of the clinical application of new antitumor drugs，and there were significant differences in cognition among clinicians of different ages，professional titles and departments. The interview results show that the hospital has established the management system of clinical application of anti-tumor drugs，and formulated the management system of clinical application of anti-tumor drugs，but there is still a gap with the management requirements in the specific implementation stage. Conclusion：The clinical doctors in this hospital have a high degree of cognition，but they still need to organize regular training and assessment，improve the working process of the professional technical team for the clinical application management of anti-tumor drugs，play the role of clinical pharmacists，and provide technical guidance and consultation in various forms to meet the needs of clinicians and improve the level of rational drug use.