Abstract:Objective：Toinvestigate the application effect of the combination teaching model of problem-based learning（PBL）plus multidisciplinary team（MDT）in the standardized training of pediatric cardiothoracic surgeons. Methods：Thirty physicians who underwent clinical standardized training at the Cardiothoracic Surgery Department of Children’s Hospital of Soochow University were taken as the research objects. They were divided into two research groups：15 in experimental group（PBL and MDT combination teaching model）and 15 in control group（PBLteaching mode）. The two groups were compared and analyzed withgrading results in basic theory，case analysis and practical operation when the training wascompleted. A questionnaire for satisfaction of teaching effect was also collected. Results：The grading results of the experimental group were（77.90 ± 2.583）and（79.40 ± 2.862）for case analysis and practical operation，respectively，which were significantly higher than（64.60 ± 1.875）and（68.30 ± 1.328），respectively，of the control group（p < 0.05）. The satisfaction of the teaching effect was also significantly higher in the experimental group than that in the control group（p < 0.05）. Conclusion：Compared to the PBL teaching mode，the combination teaching modelof PBL plus MDT can significantly improve the grading results and clinical literacy in standardized training ofphysicians，when applied in the pediatric cardiothoracic surgery teaching. It is recommended that the combination teaching model can be applied widely in order to cultivate more qualified clinical doctors.