Abstract:From Network security level protection system 1.0 standard（Information security protection of 1.0）to Network security level protection system 2.0 standard（Information security protection of 2.0），many changes have taken place in the name，classification structure and safety requirements. The technical part and the management part of the general requirements of 2.0 also have many enhancements in details. The hospital needs to check the standard 2.0，and analyze the differences between the existing information security management and 2.0 standard in order to plan and reform as soon as possible and meet 2.0 security standard. If the hospital has cloud computing，Internet of things，mobile Internet and other related applications，we also need to consider the evaluation criteria in the requirement of 2.0 security expansion，in order to improve the level of hospital information security and ensure the safe and stable operation of the hospital.