Abstract:Objective：To explore the optimization effect of Quality Control Circles of the anesthesia nurses on the anesthesia drug management. Methods：Eighteen anesthesia nurses with 3-5 years of work experience were randomly selected as the research object. Their work were improved in the followiing aspects：checking and collecting drugs，collecting basic medicine boxes，reducing leakage rate and error rate in supplementing drugs. The optimization effect of drug management in anesthesiology was observed. Results：After the optimization in the drug management of anesthesiology，the time in checking and sorting the medicine box was obviously shortened，and the drug leakage rate and misplacement rate reduced. The satisfaction of anesthesiologist on nursing work was significantly increased. Conclusions：The improvd Quality Control Circles mode has an optimization effect on the drug management in anesthesiology department.