Abstract:Objective：To provide the basic data for hospital development by analyzing the basic composition and changes of inpatients in a first-class hospital in Nanjing during 2006—2015. Method：Analyze the data of all discharged patients （age，sex and residence）by extracting from the disease report system of all discharged patients in the Health and Health Committee from 2006 to 2015. Result：More than 580，000 patients were discharged from 2006 to 2015，and the male-to-female gender ratio was 100∶108. A significant negative correlation occurred between gender ratio and the age，namely，the greater proportion of the male patients with the increasing age. The proportions of the patients in the native city，other regions of the province and the other provinces were 68.37%，16.81% and 14.82% respectively，of which the proportion of the patients from the other regions of the province and other provinces gradually increased. Conclusion：Analyzing the composition and source of patients can strengthen the hospital management and service quality.