Abstract:Objective：This study explored the role of integrated stroke management and in-hospital stroke optimization in reducing the treatment time of patients with acute ischemic stroke. Method：From July to December，2016，patients with acute ischemic stroke within 6 hours who were diagnosed in the emergency department of our hospital served as the control group. In the emergency department of our hospital from July to December 2017，patients with acute ischemic stroke within 6 hours of the disease were as the experimental group. The control group was treated according to the traditional routine of stroke. The experimental group was disposed according to the optimization process，which was to establish a three-in-one intelligent information platform for stroke and optimization of the in-hospital stroke process in each medical unit. Results：By comparing with two groups，the number of thrombolytic cases in the experimental group was higher than that in the control group（P < 0.05）. The time from onset to emergency and the time from admission to the Door to Needle Time（DNT）were both shorter than those in the control group（P < 0.01）. Conclusion：The integrated management of stroke and the optimization of in-hospital stroke process can significantly reduce the treatment time of patients with acute ischemic stroke and improve theremedy achievement ratio.