目的：探讨循证护理对改善小儿手足口病并发脑炎指标的效果。方法：选择我院于2012年6月至2014年6月期间接收的被确诊为小儿手足口病并发脑炎的100例患者为研究对象。回顾性分析2012年6月—2013年6月收治的50例患儿的临床资料，实施常规护理，设为对照组。同时回顾性分析2013年7月—2014年6月收治的50例患儿的临床资料，采用循证护理模式进行干预，设为干预组。对护理干预前、后两组患者脑脊液白细胞计数、蛋白含量、葡萄糖含量、住院时间、并发证发生率和病人及家属的满意度等一系列指标进行评估和对比。结果：干预前两组患者脑脊液白细胞计数、蛋白含量、葡萄糖含量等脑炎指标均无显著差异（P > 0.05）；干预后两组患者脑脊液白细胞计数、蛋白含量、葡萄糖含量等脑炎指标较干预前均呈现不同程度改善，差异具有统计学意义（P < 0.05）；且干预组患者脑脊液白细胞计数、蛋白含量、葡萄糖含量等脑炎指标均显著低于对照组，组间差异显著（P < 0.05）。采用不同方案进行护理干预后，干预组患者住院时间及并发证发生率显著低于对照组，家属满意程度明显优于对照组，差异具有统计学意义（P < 0.01）。结论：针对手足口病合并脑炎患儿采取循证护理措施，精心干预疗效显著，明显降低患者住院时间和并发证发生率，改善病情效果显著，提高患者对护理的满意程度。

Objective：To explore the effectiveness of evidence-based nursing on improving children patients with hand-foot-mouth disease（HFMD）complicated with encephalitis. Methods：100 cases of patients with hand-foot-and-mouth disease complicated with encephalitis from June 2012 to June 2014 in our hospital are selected as research objects. The clinical data of 50 cases of children admitted from June 2012 to June 2013 are analyzed retrospectively. They are given routine nursing care as the contrast group.At the same time，the clinical data of 50 children admitted from July 2013 to June 2014 are analyzed retrospectively. They were treated with evidence-based nursing intervention as an intervention group. A series of indexes before and after nursing intervention，such as white blood cell count，protein content，glucose content，hospitalization time，incidence rate of complications and satisfaction of family members between the two groups，are evaluated and compared. Results：Before the intervention，there is no significant difference on the white blood cell count，protein content and the content of glucose between the two groups（P > 0.05）. After the intervention，the white blood cell count，protein content and the content of glucose of the evidence-based nursing group are significantly lower than those in the contrast group（P < 0.05）. After nursing intervention with different schemes，the hospitalization time and the incidence rate of complications in the intervention group are significantly lower than those in the contrast group，and the degree of satisfaction of the family members is significantly better than that in the contrast group（P < 0.01）. Conclusion：The implementation of the evidence-based nursing can significantly shorten hospitalization time and decrease the incidence rate of HFMD complications，promote the recovery of patients and improve the satisfaction of patients. It is significantly effective and is worthy popularizing.