Abstract:Objective：Aiming at the limitation of hospital traditional medical expenses management，to explore the dynamic evaluation index and management strategy of medical expenses examination under total payment. Methods：Depth analysis of hospital medical business data by means of Delphi and comparative research methods. Build a scientific and reasonable medical expenses control platform，in order to analyze and compare the medical expenses and cost structure proportion of every department and ward，and assess the reasonableness of it. Results：Relying on medical expenses management system，the Medicare Office allocates the annual total to each ward and sets up a scientific per capita quota，in order to make efficient use of medical resources. Make use of multi-angle methods to control rising health care costs；Medical staffs’ treatment behavior tends to standardization and the phenomenon of irrational drug use has been reduced. Conclusion：Effective control of medical insurance expenses under global budge，can give full play to medical insurance on the behavior and cost of medical services guidance and supervision.