Abstract:Objective：To improve the rate of standardized PICC maintenance in patients with tumor through nursing case. Methods：The cause of non-standardized PICC maintenance in patients with tumor was analyzed through five aspects of people，machine，material，ring and method，in combination of working practice，the objective of improvement was set as standardized PICC maintenance rate of patients with tumor above 88.4%. The solution and implementation were determined，such as：establishment of system of qualification access and reduction of maintainers，enhancement of post-discharge follow-up visit and stressing of effectiveness evaluation，extension of PICC maintenance network in Yangzhou area and training of PICC maintenance knowledge，designed observation，maintained form and strict quality control，homogenized maintenance steps and evaluating the effectiveness. Results：The PICC standardized maintenance rate of patients with tumor before the improvement was elevated from 58.76% to 97.85% after the improvement. Conclusion：The PICC standardized maintenance rate of patients with tumor can be improved through nursing case activity and teamwork spirit.